摘要
连续流反应器凭借独特的优势为 API 合成带来工艺革新。其高效传质传热特性显著提升反应效率与选择性，精准的反应条件控制增强了工艺稳定性与安全性，微通道结构也为危险反应提供了可靠实现途径。连续流反应器与在线分析技术的结合实现了实时监控与优化，连续化生产模式更契合绿色化学与可持续发展理念。通过剖析连续流反应器在 API 合成中强化工艺的关键要素，探索其在该领域深度应用的方向与潜力，为推动 API 合成技术升级提供理论与实践参考。
关键词： 连续流反应器；API 合成；工艺强化；微通道；绿色化学
Abstract
Continuous flow reactors bring about process innovation API synthesis with unique advantages. Its efficient mass and heat transfer characteristics significantly enhance the efficiency and selectivity of reactions, precise control of reaction conditions enhances the stability and safety of the process and the microchannel structure also provides a reliable way to achieve dangerous reactions. The combination of continuous flow reactors and online analysis technology has realized real-time monitoring and optimization, and continuous production mode is more in line with the concept of green chemistry and sustainable development. By analyzing the key elements of intensified process of continuous flow reactors in API synthesis, the direction potential of their in-depth application in this field are explored, and theoretical and practical references are provided for promoting the technological upgrading of API synthesis.
Key words： Continuous flow; API synthesis; Process intensification; Microchannel; Green chemistry
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